Transmission & Prevention
· Injection-site skin manifestations (COVID-arm) were found in some healthcare workers who took the Pfizer (BNT162b2) mRNA COVID-19 vaccine. Dermatologists from the Ramn y Cajal University Hospital in Madrid, Spain conducted a retrospective study to investigate the “Covid-arm” skin manifestations in response to the mRNA vaccine from Pfizer (BNT162b2). In 4775 subjects, 103 (2.1%) had delayed-injection-site reactions. Histological examination of one such lesion showed evidence of perivascular inflammation and vessel dilation. While pathophysiology is unknown, authors propose several mechanisms and suggest these side effects should not preclude vaccination with the BNT162b2 vaccine.